Luchsinger V, Suárez M, Schultz R, Barraza P, Guzmán M, Terrada L, Méndez V, Kaltwasser G
Depto. de Microbiología, Facultad de Medicina, Universidad de Chile, Santiago de Chile.
Rev Med Chil. 1996 Apr;124(4):403-8.
Cytomegalovirus is the main agent of congenital viral infections. The aim of this study was to compare the incidence of congenital cytomegalovirus infections of two groups of newborns of differing socioeconomic status. Cytomegalovirus was isolated from urine or oropharingeal secretions in 218 children born in a private clinic and 471 born in a public hospital. Positive viral isolates were confirmed with indirect immunofluorescence using monoclonal antibodies. Infection was detected in 12 children (1.82%), four coming from the private clinic (1.86%) and 8 coming from the public hospital (1.81%). Ninety two percent of infected children were asymptomatic. Urine and oropharingeal secretion samples had the same yield for viral isolation. It is concluded that the incidence of congenital cytomegalovirus infection is similar to that described in developed countries.
巨细胞病毒是先天性病毒感染的主要病原体。本研究的目的是比较两组社会经济地位不同的新生儿先天性巨细胞病毒感染的发生率。从一家私立诊所出生的218名儿童和一家公立医院出生的471名儿童的尿液或口咽分泌物中分离出巨细胞病毒。使用单克隆抗体通过间接免疫荧光法确认病毒分离株呈阳性。在12名儿童（1.82%）中检测到感染，其中4名来自私立诊所（1.86%），8名来自公立医院（1.81%）。92%的受感染儿童无症状。尿液和口咽分泌物样本的病毒分离率相同。结论是先天性巨细胞病毒感染的发生率与发达国家描述的相似。
