Burumcek E, Mudun A, Karacorlu S, Arslan M O
Department of Ophthalmology, SSK Okmeydani Hospital, Istanbul, Turkey.
Ophthalmology. 1997 Apr;104(4):616-22. doi: 10.1016/s0161-6420(97)30262-0.
The authors evaluated the effect of laser photocoagulation for persistent central serous retinopathy (CSR).
The authors evaluated 45 eyes of 38 patients who had been offered laser photocoagulation for CSR that did not resolve after 4 months of observation. Sixteen eyes of 14 patients who did not accept laser photocoagulation were followed as the control group. The remaining 29 eyes of 24 patients comprised the study group. Argon green laser photocoagulation was performed on 9 eyes, dye-yellow laser photocoagulation was performed on 12 eyes, and dye-orange laser photocoagulation was performed on 8 eyes. Mean follow-up was 4.8 years (range, 1-7 years).
In the group that received laser treatment, duration of the serous detachment was shorter (P < 0.0001) and final best-corrected visual acuity (BCVA) was better (P = 0.006) than those of the control group. Although none of the eyes in the laser photocoagulation group had a recurrence, seven eyes in the control group had one or more recurrences during the mean follow-up period of 4.8 years (P = 0.0003). Although the duration of the serous detachment was shorter in the dye-yellow laser photocoagulation subgroup than in the argon green laser treatment subgroup (P = 0.01), there were no other differences between the laser photocoagulation subgroups with respect to the duration of the serous detachments or the final BCVA.
Direct laser photocoagulation of the leakage site(s) for CSR that persists for 4 months is safe and effective to shorten the duration of the serous detachment, to improve final BCVA, and to decrease the incidence of recurrence.
作者评估了激光光凝治疗持续性中心性浆液性脉络膜视网膜病变(CSR)的效果。
作者评估了38例患者的45只眼睛,这些患者因CSR在观察4个月后未缓解而接受激光光凝治疗。14例未接受激光光凝治疗的患者的16只眼睛作为对照组进行随访。其余24例患者的29只眼睛组成研究组。对9只眼睛进行了氩绿激光光凝,对12只眼睛进行了染料黄激光光凝,对8只眼睛进行了染料橙激光光凝。平均随访时间为4.8年(范围1 - 7年)。
在接受激光治疗的组中,浆液性脱离的持续时间比对照组短(P < 0.0001),最终最佳矫正视力(BCVA)比对照组好(P = 0.006)。虽然激光光凝组中没有眼睛复发,但在平均4.8年的随访期内,对照组有7只眼睛出现了一次或多次复发(P = 0.0003)。虽然染料黄激光光凝亚组中浆液性脱离的持续时间比氩绿激光治疗亚组短(P = 0.01),但在浆液性脱离持续时间或最终BCVA方面,激光光凝亚组之间没有其他差异。
对持续4个月的CSR渗漏部位进行直接激光光凝,对于缩短浆液性脱离的持续时间、改善最终BCVA以及降低复发率是安全有效的。