Ahnlide I, Bjellerup M
Department of Dermatology, Malmö University Hospital, Sweden.
Acta Derm Venereol. 1997 Mar;77(2):144-5. doi: 10.2340/0001555577144145.
The prevalence of leg ulcer disease is high and the health care costs are extensive. Effective therapy is essential to minimise the health care costs and suffering on the part of the patient. If possible, first and foremost, therapy should be aimed at correcting the underlying aetiological defect causing the ulcer. After this has been considered, one of the local therapeutic options is skin grafting using small full thickness skin grafts, i.e. pinch grafting. During the period 1991-1993 altogether 145 therapy-resistant leg ulcers were treated with the pinch graft method at the Department of Dermatology, Malmö University Hospital. The healing rate after 3 months was studied in retrospect. An overall healing rate of 36% was found. The healing rate was dependent on aetiological diagnosis, with a healing rate of 22% in venous and 50% in arterial ulcers. The pinch graft method, which may be used on an out-patient basis offers a simple and relatively effective option in the treatment of leg ulcers. It is recommended as first line skin grafting method. As second line skin grafting method split thickness skin graft, with or without ulcer excision, is recommended.
腿部溃疡疾病的患病率很高，医疗费用也很高。有效的治疗对于将医疗费用降至最低以及减轻患者的痛苦至关重要。如果可能的话，首先，治疗应旨在纠正导致溃疡的潜在病因缺陷。在考虑到这一点之后，局部治疗选择之一是使用小全层皮肤移植进行皮肤移植，即点状植皮。1991年至1993年期间，马尔默大学医院皮肤科共对145例难治性腿部溃疡采用点状植皮法进行治疗。回顾性研究了3个月后的愈合率。发现总体愈合率为36%。愈合率取决于病因诊断，静脉性溃疡的愈合率为22%，动脉性溃疡的愈合率为50%。点状植皮法可在门诊使用，是治疗腿部溃疡的一种简单且相对有效的选择。它被推荐为一线皮肤移植方法。作为二线皮肤移植方法，推荐采用有或无溃疡切除的中厚皮片移植。
