Filiaci F, lo Vecchio A, Zambetti G, Luce M, Romeo R
ENT Department, University of Rome La Sapienza, Italy.
Allergol Immunopathol (Madr). 1997 Jan-Feb;25(1):18-22.
Reinke's edema is characterized by swelling of the vocal cords, which generally is bilateral but often is more pronounced in one cord. The disease is named after the anatomist Reinke, who undertook a morphological study of the subepithelial connective tissue of the vocal cords in order to investigate edematous spread. In general, swelling of the vocal cords develops gradually and may increase considerably over months or even years. To evaluate an eventual relation ship between airways (nasal and bronchial) and Reinke's edema of the vocal cords, the authors studied 9 subjects suffering from Reinke's edema. These patients underwent to an accurate clinical history, skin-test for inhalant pollens and mycetes to evaluate the eventual presence of specific allergies, non-specific nasal provocation test with Histamine, baseline RRM to evaluate the non-specific nasal hypersensitivity and besides the RRM values has been considered the number of sneezes after Histamine stimulation, finally a bronchial provocation test with ultrasonic fog to evaluate the presence of non-specific hypersensitivity of the lower airways.
任克氏水肿的特征是声带肿胀，通常为双侧性，但一侧声带的肿胀往往更明显。该疾病以解剖学家任克的名字命名，任克对声带的上皮下结缔组织进行了形态学研究，以调查水肿的蔓延情况。一般来说，声带肿胀是逐渐发展的，可能在数月甚至数年中显著加重。为了评估气道（鼻腔和支气管）与任克氏声带水肿之间的潜在关系，作者对9例任克氏水肿患者进行了研究。这些患者接受了详细的临床病史询问、吸入性花粉和真菌的皮肤试验，以评估是否存在特异性过敏，用组胺进行非特异性鼻腔激发试验，进行基础鼻阻力测量以评估非特异性鼻腔超敏反应，除了鼻阻力测量值外，还记录了组胺刺激后的喷嚏次数，最后用超声雾化进行支气管激发试验，以评估下呼吸道非特异性超敏反应的存在情况。
