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格洛斯特郡的急性下肢缺血

Acute leg ischaemia in Gloucestershire.

作者信息

Davies B, Braithwaite B D, Birch P A, Poskitt K R, Heather B P, Earnshaw J J

机构信息

Gloucestershire Royal Hospital, UK.

出版信息

Br J Surg. 1997 Apr;84(4):504-8.

PMID:9112902
Abstract

BACKGROUND

Acute leg ischaemia is both life threatening and limb threatening. This audit was designed to determine the incidence and outcome of acute leg ischaemia in a single county.

METHODS

Using multisource data collection for a 1-year interval in 1994 all patients with acute leg ischaemia were identified prospectively using hospital and general practice records in the county of Gloucestershire, population 540,000.

RESULTS

Seventy-seven patients with 84 events of acute leg ischaemia were identified, giving an incidence of one per 7000 per year rising to one per 6000 per year when bypass graft occlusions were included. All but four patients were treated in hospital. Sixteen of 80 hospital events involved conservative treatment; after 30 days nine patients had died and two required amputation. The remaining five patients had borderline ischaemic rest pain and accepted their symptoms without intervention. Sixty-four of 80 events were managed by either primary surgery and angioplasty (n = 31) or thrombolysis (n = 33). The 30-day outcome in patients treated actively was: limb salvage in 50 (78 per cent), amputation in four (6 per cent) and death in ten (16 per cent).

CONCLUSION

In Gloucestershire almost all cases of acute leg ischaemia are managed by, or discussed with vascular surgeons. A flexible integrated policy of surgery and peripheral thrombolysis has resulted in a limb salvage rate of 78 per cent in patients suitable for active treatment.

摘要

背景

急性下肢缺血既危及生命,也威胁肢体。本次审计旨在确定一个单一郡县急性下肢缺血的发病率及转归情况。

方法

利用多源数据收集,对1994年为期1年的时间段进行研究,通过格洛斯特郡县(人口54万)的医院及全科医疗记录,前瞻性地识别出所有急性下肢缺血患者。

结果

共识别出77例患者发生84次急性下肢缺血事件,发病率为每年万分之一,若将旁路移植血管闭塞纳入计算,则升至每年万分之一点七。除4例患者外,其余均在医院接受治疗。80次住院事件中有16次采用保守治疗;30天后,9例患者死亡,2例需要截肢。其余5例患者有临界性缺血性静息痛,未接受干预而接受了自身症状。80次事件中有64次通过一期手术和血管成形术(n = 31)或溶栓治疗(n = 33)处理。积极治疗患者的30天转归情况为:50例(78%)肢体得以挽救,4例(6%)截肢,10例(16%)死亡。

结论

在格洛斯特郡,几乎所有急性下肢缺血病例均由血管外科医生处理或会诊。灵活的手术与外周溶栓综合策略使适合积极治疗的患者肢体挽救率达到78%。

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