Ambrosetti P, Grossholz M, Becker C, Terrier F, Morel P
Division of General Surgery, University Hospital of Geneva, Switzerland.
Br J Surg. 1997 Apr;84(4):532-4. doi: 10.1046/j.1365-2168.1997.02576.x.
The use of computed tomography (CT) in acute left colonic diverticulitis remains controversial. The purpose of this study was to define the value of CT both during the acute phase of inflammation and, later, to indicate secondary complications after successful medical treatment.
Some 423 patients with radiologically or histologically proven diverticulitis were studied prospectively from 1986 to 1995. Diverticulitis was considered moderate when CT showed localized thickening of the colonic wall (5 mm or more) and inflammation of pericolic fat; it was considered severe when abscess and/or extraluminal air and/or extraluminal contrast were observed.
The sensitivity of CT was 97 per cent. Of 42 patients who failed conservative treatment, 32 had severe diverticulitis on CT, compared with 74 (24 per cent) of 303 who had successful conservative treatment (P < 0.0001). After a median follow-up of 46 months, 60 (20 per cent) of 300 patients had secondary complications despite initially successful conservative treatment: 28 (47 per cent) of these had initial severe diverticulitis on CT compared with 44 (19 per cent) of 236 patients who had no complications (P < 0.0001).
Abscess formation and extracolonic contrast or gas are findings that may be used to predict failure of medical treatment during the first admission and a high risk of secondary complications after initially successful medical management of acute diverticulitis.
计算机断层扫描(CT)在急性左半结肠憩室炎中的应用仍存在争议。本研究的目的是明确CT在炎症急性期的价值,以及在成功的药物治疗后提示继发性并发症。
1986年至1995年对约423例经放射学或组织学证实的憩室炎患者进行了前瞻性研究。当CT显示结肠壁局限性增厚(5毫米或更厚)和结肠周围脂肪炎症时,憩室炎被认为是中度;当观察到脓肿和/或腔外气体和/或腔外造影剂时,则被认为是重度。
CT的敏感性为97%。在42例保守治疗失败的患者中,32例CT显示为重度憩室炎,而在303例保守治疗成功的患者中,有74例(24%)显示为重度憩室炎(P<0.0001)。中位随访46个月后,300例患者中有60例(20%)尽管最初保守治疗成功但仍出现了继发性并发症:其中28例(47%)最初CT显示为重度憩室炎,而236例无并发症的患者中有44例(19%)(P<0.0001)。
脓肿形成、结肠外造影剂或气体是可用于预测首次入院时药物治疗失败以及急性憩室炎最初成功的药物治疗后继发性并发症高风险的表现。