O'Malley M
Employee Health Services, University of California, Davis 95616, USA.
Lancet. 1997 Apr 19;349(9059):1161-6. doi: 10.1016/S0140-6736(96)07222-4.
Pesticide exposures cause disorders varying from straightforward topical irritant reactions, such as those to synthetic pyrethroid insecticides, to complex systemic illness, such as that resulting from cholinesterase inhibition by organophosphate pesticides. The acute illness syndromes associated with pesticides most commonly encountered by clinicians are illustrated here by cases reported to the California Pesticide Illness Surveillance Program. The issues raised include asthma associated with exposure to contaminants in organophosphate insecticides, systemic toxicity of ingested pyrethroids (in children), and illnesses associated with spills or misuse of fumigants.
接触农药会引发各种病症,从直接的局部刺激反应,如接触合成拟除虫菊酯类杀虫剂所引起的反应,到复杂的全身性疾病,如有机磷农药抑制胆碱酯酶所导致的疾病。临床医生最常遇到的与农药相关的急性病症综合征,在此通过向加利福尼亚农药疾病监测项目报告的病例进行说明。所提出的问题包括与接触有机磷杀虫剂中的污染物相关的哮喘、(儿童)摄入拟除虫菊酯类的全身毒性,以及与熏蒸剂泄漏或误用相关的疾病。