Bilder R M
Hillside Hospital Division of Long Island Jewish Medical Center, Glen Oaks, New York.
Can J Psychiatry. 1997 Apr;42(3):255-64. doi: 10.1177/070674379704200303.
To review the roles played by neurocognitive assessment in the treatment of schizophrenia and in the design of treatment research strategies.
A review of the literature and summaries of clinical and research implications are presented, with directions for future research.
Neurocognitive deficits are now targets of antipsychotic drug treatment and should increasingly be used to refine both theory and clinical practice by considering the effects of treatments at the level of neural systems.
Efforts to bridge the gaps between preclinical and clinical assessments should yield large rewards in drug development and individualized treatment strategies. Functional neuroimaging may play a major role in these developments.
回顾神经认知评估在精神分裂症治疗及治疗研究策略设计中所起的作用。
对文献进行综述，并呈现临床及研究意义总结以及未来研究方向。
神经认知缺陷现已成为抗精神病药物治疗的靶点，通过考虑治疗在神经系统层面的作用，应越来越多地用于完善理论和临床实践。
弥合临床前评估与临床评估之间差距的努力，有望在药物研发和个体化治疗策略方面带来巨大回报。功能神经影像学可能在这些进展中发挥重要作用。
