Cervoni L, Artico M, Salvati M, Carloia S
Divisione di Neurochirurgia, Istituto Neurologico Mediterraneo Neuromed, IRCCS, Pozzilli, Italy.
Ital J Neurol Sci. 1997 Feb;18(1):37-40. doi: 10.1007/BF02106229.
We report the case of a 62-year-old woman, who had a 4-year history of progressive visual acuity deficit. On neurological examination, visual acuity was 5/20 in the right and 4/20 in the left eye. A hormonal study revealed hypophyseal hypofunction. CT and MRI scans showed an intra-suprasellar cystic lesion, hyperintense in T1 and hyperintense in T2-weighted sequences. At surgery, the cyst wall was opened and the cavity placed in communication with the subarachnoid space. Histological examination showed a Rathke's cleft cyst. After four years of follow-up the patient's visual deficit remained unchanged, whereas the results of the hormonal assays were normal. An MRI scan confirmed the absence of the cyst. We review 216 reported cases of Rathke's cyst and discuss its pathogenesis, clinical features and treatment.
我们报告了一例62岁女性患者,她有4年进行性视力减退病史。神经系统检查显示,右眼视力为5/20,左眼视力为4/20。激素检查显示垂体功能减退。CT和MRI扫描显示鞍内-鞍上囊性病变,在T1加权序列中呈高信号,在T2加权序列中也呈高信号。手术时,打开囊肿壁,使囊腔与蛛网膜下腔相通。组织学检查显示为拉克氏囊肿。经过四年的随访,患者的视力缺损没有变化,而激素检测结果正常。MRI扫描证实囊肿已消失。我们回顾了216例已报道的拉克氏囊肿病例,并讨论了其发病机制、临床特征和治疗方法。