Baker B, Zambryski P, Staskawicz B, Dinesh-Kumar S P
Department of Plant and Microbial Biology, University of California, Berkeley, CA 94720, USA.
Science. 1997 May 2;276(5313):726-33. doi: 10.1126/science.276.5313.726.
Analysis of viral and bacterial pathogenesis has revealed common themes in the ways in which plants and animals respond to pathogenic agents. Pathogenic bacteria use macromolecule delivery systems (types III and IV) to deliver microbial avirulence proteins and transfer DNA-protein complexes directly into plant cells. The molecular events that constitute critical steps of plant-pathogen interactions seem to involve ligand-receptor mechanisms for pathogen recognition and the induction of signal transduction pathways in the plant that lead to defense responses. Unraveling the molecular basis of disease resistance pathways has laid a foundation for the rational design of crop protection strategies.
对病毒和细菌发病机制的分析揭示了植物和动物对病原体作出反应的方式中存在的共同主题。致病细菌利用大分子输送系统（III型和IV型）将微生物无毒蛋白和转移DNA-蛋白质复合物直接输送到植物细胞中。构成植物-病原体相互作用关键步骤的分子事件似乎涉及病原体识别的配体-受体机制以及植物中导致防御反应的信号转导途径的诱导。阐明抗病途径的分子基础为合理设计作物保护策略奠定了基础。
