Marks L B, Prosnitz L R
Department of Radiation Oncology, Duke University Medical Center, Durham, North Carolina, USA.
Surg Oncol Clin N Am. 1997 Apr;6(2):359-79.
Data from randomized and nonrandomized studies demonstrate that the addition of breast irradiation after local excision of invasive and noninvasive breast cancers markedly reduces the breast failure rate. Local excision with breast irradiation remains the standard approach for breast-conserving therapy for both invasive and noninvasive cancers. Some data suggest that there might be patient subgroups that could be treated with local excision without radiotherapy, but additional studies are necessary to better define these groups.
随机和非随机研究的数据表明，在浸润性和非浸润性乳腺癌局部切除术后加用乳房照射可显著降低乳房复发率。局部切除加乳房照射仍然是浸润性和非浸润性癌症保乳治疗的标准方法。一些数据表明，可能存在无需放疗仅行局部切除即可治疗的患者亚组，但需要更多研究来更好地界定这些亚组。
