Lopez M J, Smart C R
Department of Surgery, Tufts University School of Medicine, Boston, Massachusetts, USA.
Surg Oncol Clin N Am. 1997 Apr;6(2):393-401.
Since the 1960s, the potential benefits of early detection of breast cancer through screening with physical examination and mammography have been studied. In a mass screening study begun in 1973 by the Breast Cancer Detection Demonstration Project (BCDDP), mammography detected 90% of the cancers that were diagnosed. Of the women aged 35 to 74 years from the BCDDP study who were diagnosed with minimal breast cancer, the 20-year cumulative breast cancer survival rates were 95.8% for 469 women with in situ breast cancer and 82.8% for 769 women with invasive breast cancers 1 cm or smaller in size.
自20世纪60年代以来,通过体格检查和乳房X光检查进行筛查以早期发现乳腺癌的潜在益处已得到研究。在1973年由乳腺癌检测示范项目(BCDDP)启动的一项大规模筛查研究中,乳房X光检查检测出了90%已确诊的癌症。在BCDDP研究中年龄在35至74岁之间被诊断为微小乳腺癌的女性中,469例原位乳腺癌女性的20年累积乳腺癌生存率为95.8%,769例肿瘤大小为1厘米或更小的浸润性乳腺癌女性的20年累积乳腺癌生存率为82.8%。