Sidney K H, Shephard R J
Br Heart J. 1977 Oct;39(10):1114-20. doi: 10.1136/hrt.39.10.1114.
Electrocardiograms (CM5 lead, where one lead is attached in the V5 position and one at the manubrium sterni, with the neutral lead on the back of the neck) have been recorded from 14 men and 25 women aged 60 to 75 years, at rest, during progressive bicycle ergometer exercise to 75 to 85 per cent maximum oxygen intake, and during the subsequent recovery phase. Earlier studies showing a high frequency of ischaemic electrocardiographic abnormalities in women are confirmed; it is suggested that this may reflect a high work load per unit mass of myocardium. Training induces an elevation of the ST segment at rest and during recovery, with a reduction in ST depression during work at a given heart rate, the exercise changes being related to the intensity and frequency of training selected by the subject. Possible explanations of the response to regular exercise include not only the development of the collateral circulation, but also a lessening of the hyperkalaemia of effort and a reduction in the work load per unit mass of myocardium secondary to hypertrophy or a change in the average dimensions of the heart.
已对14名男性和25名年龄在60至75岁之间的女性进行了心电图记录(CM5导联,其中一个导联连接在V5位置,另一个连接在胸骨柄处,中性导联置于颈部后方),记录时段包括静息时、在自行车测力计上进行递增运动直至最大摄氧量的75%至85%时,以及随后的恢复阶段。早期研究表明女性缺血性心电图异常的发生率很高,这一结果得到了证实;有人认为,这可能反映了心肌单位质量的高工作负荷。训练会使静息时和恢复期间的ST段抬高,在给定心率下工作时ST段压低程度降低,运动变化与受试者选择的训练强度和频率有关。对规律运动反应的可能解释不仅包括侧支循环的发展,还包括运动性高钾血症的减轻以及心肌单位质量工作负荷的降低,后者继发于心室肥厚或心脏平均尺寸的改变。