Hürzeler D
Schweiz Rundsch Med Prax. 1979 Sep 11;68(37):1188-91.
After drawing attention to the literature concerning the use of cryotherapy in the field of ORL, the results of this therapy based on 40 cases, involving a total of 73 applications, are set out. Of mucous membrane affections otherwise resistant to therapy and inclined to recidivation, it was possible to cure two thirds of the cases and achieved an improvement in five further cases, giving altogether more than three quarters of the cases showing favourable results. An appliance was used which achieved a temperature of -40 degrees C at the tip of the probe, using the Joule-Thomson principle with expansion of nitrous oxide. This temperature is sufficiently low to effect surface changes, but is not so low as to cause destruction of larger amounts of tissue. Cryotherapy should occupy a permanent place in medical practice.
在提请注意耳鼻喉科领域中有关冷冻疗法应用的文献后，本文阐述了基于40例患者、共73次应用的该疗法结果。对于其他治疗方法难以奏效且易于复发的黏膜疾病，有三分之二的病例得以治愈，另有5例病情得到改善，总计超过四分之三的病例取得了良好效果。使用了一种依据焦耳 - 汤姆逊原理利用一氧化二氮膨胀使探头尖端达到 -40摄氏度的器械。该温度足以引发表面变化，但又不至于低到造成大量组织破坏。冷冻疗法应在医疗实践中占据一席之地。
