McIsaac W J, Goel V, Slaughter P M, Parsons G W, Woolnough K V, Weir P T, Ennet J R
Institute for Clinical Evaluative Sciences, North York, Ont.
Can Fam Physician. 1997 Mar;43:485-93.
To provide evidence-based answers to clinical questions posed by family physicians about Group A streptococcus pharyngitis and to further understanding of why management is controversial.
Evidence from randomized trials was not found for most questions. The most critical information came from high-quality community prevalence studies and criterion standard studies of physician clinical judgement.
Expert recommendations for physician management are not likely to help prevent rheumatic fever, as most people with sore throats do not seek medical care. Current clinical practices result in overuse of antibiotics because accuracy of clinical judgment is limited.
Costs associated with visits for upper respiratory infections as well as increasing antibiotic resistance necessitate reconsidering the current clinical approach. An alternative management strategy is presented in part 2.
为家庭医生提出的关于A组链球菌性咽炎的临床问题提供循证答案,并进一步理解为何管理存在争议。
大多数问题未找到随机试验的证据。最关键的信息来自高质量的社区患病率研究和医生临床判断的标准对照研究。
专家对医生管理的建议不太可能有助于预防风湿热,因为大多数喉咙痛的人不会寻求医疗护理。由于临床判断的准确性有限,目前的临床实践导致抗生素过度使用。
上呼吸道感染就诊的相关费用以及抗生素耐药性增加,有必要重新考虑当前的临床方法。第2部分提出了一种替代管理策略。