Reid G, van der Mei H C, Tieszer C, Busscher H J
Department of Microbiology and Immunology, University of Western Ontario, London, Canada.
FEMS Immunol Med Microbiol. 1996 Dec 31;16(3-4):159-62. doi: 10.1111/j.1574-695X.1996.tb00132.x.
Five well-characterized urinary and fecal isolates of Escherichia coli were found to be hydrophilic irrespective of their serotypes and their ability to express fimbriae. All the strains were able to adhere to silicone latex urinary catheters, although strain 917, which expressed type P fimbriae as its only adhesin, adhered poorly. Although specific adhesins, particularly fimbriae, have been shown to mediate adhesion of E. coli to uroepithelial cells, they do not mediate specific adhesion onto urinary catheter material. The overall surfaces of the strains, tested using microelectrophoresis as a function of pH and X-ray photoelectron spectroscopy, were not significantly different, thus suggesting more non-specific adhesion mechanisms to urinary catheters.
发现五株特征明确的大肠杆菌尿液和粪便分离株具有亲水性，与它们的血清型及其表达菌毛的能力无关。所有菌株都能够粘附在硅橡胶导尿管上，尽管仅表达P型菌毛作为唯一粘附素的917菌株粘附性较差。虽然已经证明特定的粘附素，特别是菌毛，可介导大肠杆菌与尿道上皮细胞的粘附，但它们并不介导在导尿管材料上的特异性粘附。使用微电泳作为pH值和X射线光电子能谱的函数对菌株的整体表面进行测试，结果没有显著差异，因此表明对导尿管存在更多非特异性粘附机制。
