Montague P R
Division of Neuroscience, Baylor College of Medicine, Houston, TX 77030, USA.
J Physiol Paris. 1996;90(3-4):239-42. doi: 10.1016/s0928-4257(97)81431-3.
It has been proposed that volumes of neural tissue may represent important processing elements. This viewpoint suggests one way that populations of synaptic elements cooperate to implement important computational capacities. I extend this view by proposing a set of computational functions for the extracellular space shared by a local population of synapses. The critical hypothesis is the existence of a hypothetical 'fluid' resource present outside synapses that must be internalized in order for a synapse to function. I outline some of the consequences of assuming that such a resource is in limited supply on short time scales.
有人提出神经组织的体积可能代表重要的处理元件。这一观点暗示了一种突触元件群体合作以实现重要计算能力的方式。我通过为局部突触群体共享的细胞外空间提出一组计算功能来扩展这一观点。关键假设是存在一种假设的“流体”资源,它存在于突触之外,突触要发挥功能就必须将其内化。我概述了假设这种资源在短时间尺度上供应有限所带来的一些后果。