Usami S, Ottersen O P
Department of Otorhinolaryngology, Hirosaki University School of Medicine, Japan.
Brain Res. 1996 Dec 2;742(1-2):43-9. doi: 10.1016/s0006-8993(96)01001-3.
The cellular and subcellular localization of aspartate in the guinea pig inner ear was studied by means of quantitative postembedding cytochemistry. High levels of aspartate immunoreactivity were found in neuronal compartments, including all types of hair cells, and afferent and efferent nerve fibers. In addition, sub-basilar tympanic cells, interdental cells, and the mesothelial cells in the Reissner's membrane were strongly immunoreactive. The present immunocytochemical results are consistent with the idea that aspartate is involved in neurotransmission in the inner ear, but also point to possible metabolic roles of aspartate.
通过定量包埋后细胞化学方法研究了豚鼠内耳中天冬氨酸的细胞和亚细胞定位。在神经元区域发现了高水平的天冬氨酸免疫反应性，包括所有类型的毛细胞以及传入和传出神经纤维。此外，基底鼓室下细胞、齿间细胞和Reissner膜中的间皮细胞具有强烈的免疫反应性。目前的免疫细胞化学结果与天冬氨酸参与内耳神经传递的观点一致，但也指出了天冬氨酸可能的代谢作用。
