Katzelnick D J, Kobak K A, Greist J H, Jefferson J W, Henk H J
Dean Foundation for Health, Research, and Education, Middleton, WI 53562, USA.
Psychiatr Serv. 1997 Jan;48(1):59-64. doi: 10.1176/ps.48.1.59.
The study examined the impact of identifying and treating depression among patients who had a history of high medical expenditures. Effects on service use, disability, and quality of life were measured.
A total of 786 high users of services from two primary care clinics and an equal number of randomly selected patients who were not high users were screened for depression using the Medical Outcomes Study (MOS) depression screen. High-user patients who screened positive were subsequently seen by their primary care physician for a diagnostic interview. The 20 patients with a confirmed diagnosis of depression were offered open-label antidepressant treatment by their primary care physician for six months.
All 20 patients completed the six-month study. Treatment resulted in significant reductions in depression and significant improvements in quality of life in the areas of social functioning, general health, mental health, physical functioning, emotional role functioning, and vitality. Days of missed work per month were reduced, and the percentage of patients who reported not being at all impaired by their depression at work increased. Costs for service use fell from $13.28 to $6.75 per day; when costs for the treatment study were added, the daily service use cost was $12.55.
Identification and treatment of depression among patients with a history of high medical expenditures improved depression and increased work productivity and quality of life. Service use decreased with treatment. A larger sample and control group are needed to determine if treatment is associated with a statistically significant decrease in medical expenditures.
本研究考察了对有高医疗费用支出史的患者识别并治疗抑郁症的影响。测量了对服务使用、残疾状况和生活质量的影响。
使用医学结局研究(MOS)抑郁筛查量表,对来自两家初级保健诊所的786名高服务使用者以及同等数量随机选取的非高服务使用者进行抑郁症筛查。筛查呈阳性的高服务使用者随后由其初级保健医生进行诊断访谈。确诊为抑郁症的20名患者由其初级保健医生提供为期六个月的开放标签抗抑郁治疗。
所有20名患者均完成了为期六个月的研究。治疗使抑郁症显著减轻,在社会功能、总体健康、心理健康、身体功能、情感角色功能和活力等生活质量领域有显著改善。每月旷工天数减少,报告在工作中完全未受抑郁症影响的患者比例增加。服务使用成本从每天13.28美元降至6.75美元;加上治疗研究的成本后,每日服务使用成本为12.55美元。
对有高医疗费用支出史的患者识别并治疗抑郁症改善了抑郁状况,提高了工作效率和生活质量。治疗后服务使用减少。需要更大的样本和对照组来确定治疗是否与医疗费用的统计学显著降低相关。