Dhopesh V, Macfadden A, Maany I, Gamble G
Department of Psychiatry, Veterans Affairs Medical Center, Philadelphia, PA 19104, USA.
Psychiatr Serv. 1997 Jan;48(1):95-7. doi: 10.1176/ps.48.1.95.
The study used the United Parkinson's Disease Scale to compare parkinsonian signs and symptoms among 19 patients in long-term neuroleptic therapy who had a history of cocaine abuse with those among 24 similar patients with no history of cocaine use. There was no significant difference between the two groups' scores. The results suggest that chronic cocaine abuse is not a risk factor for parkinsonism among subjects in long-term neuroleptic therapy.
该研究使用统一帕金森病评定量表，比较了19名有可卡因滥用史且长期接受抗精神病药物治疗的患者与24名无可卡因使用史的类似患者之间的帕金森氏体征和症状。两组得分无显著差异。结果表明，在长期接受抗精神病药物治疗的受试者中，慢性可卡因滥用不是帕金森病的危险因素。
