Dudorkinová D
II. patologickoanatomický ústav 1. LF UK a VFN, Praha.
Cesk Patol. 1996 Aug;32(3):105-9.
Two cases of a rare neuroectodermal compound tumor (pheochromocytoma-ganglioneuroma) of the adrenal were described. They were found in 2.85% of all neuroectodermal adrenal tumors investigated during 20 years. One tumor was diagnosed bioptically in a patient with hypertension. The other one was found incidentally in an autopsy. In both of the them, the major part was feochromocytoma. The structures of ganglioneuroma were only focal. Chromogranin A was relatively strongly positive in pheochromocytes which contained neurosecretory granules. In gangliocytes, the neuron-specific enolase was strongly and serotonin weakly expressed.
描述了两例罕见的肾上腺神经外胚层复合肿瘤(嗜铬细胞瘤-神经节神经瘤)。它们在20年期间所研究的所有肾上腺神经外胚层肿瘤中占2.85%。其中一例肿瘤通过活检在一名高血压患者中得以诊断。另一例在尸检时偶然发现。在这两例肿瘤中,主要部分是嗜铬细胞瘤。神经节神经瘤结构仅呈局灶性。嗜铬粒蛋白A在含有神经分泌颗粒的嗜铬细胞中呈相对强阳性。在神经节细胞中,神经元特异性烯醇化酶呈强表达,而血清素呈弱表达。