Zámecník M, Michal M, Fakan F
Katedra patológie IVZ, Bratislava, Slovenská republika.
Cesk Patol. 1996 Aug;32(3):115-7.
Chondroid lipoma had not been defined until 1993. Here presented case was a 30-year old woman with a well limited soft tissue tumour of the left thigh. In histology, the encapsulated tumour consisted of mature adipocytes in common lipoma like areas and of a chondroid component in which lipoblastic or hibernoma like cells were surrounded by a myxohyaline matrix. Both components were connected and mutually transient. Tumour cells showed S-100 protein and laminin positivity in immunohistochemistry. Cells of the chondroid component had distinct ultrastructural features of adipose and cartilagineous differentiation. Chondroid lipoma is a benign tumour which is to be distinguished from extraskeletal myxoid chondrosarcoma and myxoid liposarcoma.
软骨样脂肪瘤直到1993年才被定义。本文报道的病例是一名30岁女性，左大腿有一个界限清楚的软组织肿瘤。组织学上，包膜完整的肿瘤在常见脂肪瘤样区域由成熟脂肪细胞组成，并有一个软骨样成分，其中脂肪母细胞或冬眠瘤样细胞被黏液透明质酸基质包围。两种成分相连且相互移行。免疫组化显示肿瘤细胞S-100蛋白和层粘连蛋白呈阳性。软骨样成分的细胞具有脂肪和软骨分化的独特超微结构特征。软骨样脂肪瘤是一种良性肿瘤，需与骨外黏液样软骨肉瘤和黏液样脂肪肉瘤相鉴别。
