大肠杆菌中醌池组成的需氧依赖性变化。醌生物合成转录后调控的证据。
Aeration-dependent changes in composition of the quinone pool in Escherichia coli. Evidence of post-transcriptional regulation of the quinone biosynthesis.
作者信息
Shestopalov A I, Bogachev A V, Murtazina R A, Viryasov M B, Skulachev V P
机构信息
Department of Bioenergetics, Belozersky Institute of Physico-Chemical Biology, Moscow State University, Russia.
出版信息
FEBS Lett. 1997 Mar 10;404(2-3):272-4. doi: 10.1016/s0014-5793(97)00143-9.
The aeration-dependent changes in content of various quinones in Escherichia coli were found to be unaffected by a prokaryotic translation inhibitor chloramphenicol. In addition, this process was shown to be completely intact in cells with mutated fnr, arc and appY loci. It is assumed that E. coli possesses a special system of oxygen-dependent post-transcriptional regulation of the quinone biosynthetic pathways.
研究发现，大肠杆菌中各种醌含量的需氧依赖性变化不受原核翻译抑制剂氯霉素的影响。此外，在fnr、arc和appY基因座发生突变的细胞中，这一过程显示完全正常。据推测，大肠杆菌拥有一种特殊的醌生物合成途径的氧依赖性转录后调控系统。
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