Obraztsov N V, Khalilov E M
Biofizika. 1977 Sep-Oct;22(5):937-9.
Effect of steroid hormones on peroxidation of lipids of rats' liver endoplasmic reticulum was studied. Accumulation of peroxidation products was measured by the change in chemoluminescence intensity and by the rate of malone dealdehydeformation. It was shown that typical antioxidants--estrogenes were the inhibitors of NADH-H and ascorbate-dependent systems of lipid peroxidation in rat liver microsomes, the enzymatic system being the most sensitive one.
研究了类固醇激素对大鼠肝脏内质网脂质过氧化作用的影响。通过化学发光强度的变化和丙二醛形成速率来测定过氧化产物的积累。结果表明，典型的抗氧化剂——雌激素是大鼠肝脏微粒体中NADH-H和抗坏血酸依赖性脂质过氧化系统的抑制剂，其中酶系统最为敏感。
