Blanc D S, Parret T, Janin B, Raselli P, Francioli P
Division autonome de médecine préventive hospitalière, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland.
Infect Control Hosp Epidemiol. 1997 Feb;18(2):134-6. doi: 10.1086/647569.
During a 6-month period, two genetically distinct clones were isolated from 65% of patients with Pseudomonas aeruginosa isolated from bronchial specimens obtained during or after bronchoscopy. This epidemic was due to contamination of bronchoscopes by washing machines. After reintroduction of manual disinfection of endoscopes, a significant decrease in the incidence of the epidemic clones was observed, but the incidence of nonepidemic P aeruginosa did not change. The distinction between sporadic and epidemic cases was possible only with the use of a molecular typing method (ribotyping).
在6个月期间，从支气管镜检查期间或之后获得的支气管标本中分离出的铜绿假单胞菌患者中，65%的患者分离出了两个基因不同的克隆株。此次流行是由于支气管镜被洗衣机污染所致。重新采用内镜手动消毒后，流行克隆株的发生率显著下降，但非流行的铜绿假单胞菌的发生率未发生变化。只有使用分子分型方法（核糖体分型）才能区分散发病例和流行病例。
