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结核性脑膜炎的预后:一项多因素分析。

Prognosis of tuberculous meningitis: a multivariate analysis.

作者信息

Misra U K, Kalita J, Srivastava M, Mandal S K

机构信息

Department of Neurology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India.

出版信息

J Neurol Sci. 1996 Apr;137(1):57-61. doi: 10.1016/0022-510x(95)00334-x.

DOI:10.1016/0022-510x(95)00334-x
PMID:9120488
Abstract

Twenty-six clinical, laboratory and CT scan features in 49 patients with tuberculous meningitis (TBM) were analysed to identify the parameters of prognostic significance. Employing univariate analysis, seven variables were found to correlate with three month outcome; these variables included the stage of TBM on admission, focal weakness, Glasgow coma scale (GCS), incontinence, infarction, hydrocephalus and shunt surgery. Analysing all 26 variables, a conditional logistic regression model was derived. In this model stage of TBM, age, focal weakness, cranial nerve palsy and hydrocephalus were found to be contributing to the three month outcome of TBM patients as assessed by the Barthel index.

摘要

对49例结核性脑膜炎(TBM)患者的26项临床、实验室及CT扫描特征进行分析,以确定具有预后意义的参数。采用单因素分析,发现7个变量与3个月的预后相关;这些变量包括入院时TBM的分期、局灶性无力、格拉斯哥昏迷量表(GCS)、大小便失禁、梗死、脑积水和分流手术。分析所有26个变量,得出一个条件逻辑回归模型。在该模型中,通过Barthel指数评估发现,TBM分期、年龄、局灶性无力、脑神经麻痹和脑积水对TBM患者的3个月预后有影响。

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