Taous Abdellah, Berri Maha Ait, Boulahri Tarik, Traibi Imane, Amrani Hicham Naji, Rouimi Abdelhadi
Service de Neurologie, Hôpital Militaire Moulay Ismail, Meknès, Maroc.
Service de Pneumologie, Hôpital Militaire Moulay Ismail, Meknès, Maroc.
Pan Afr Med J. 2022 Dec 30;43:214. doi: 10.11604/pamj.2022.43.214.18038. eCollection 2022.
The purpose of this study was to investigate the epidemiological, clinical, paraclinical, therapeutic and evolutionary profile of patients with neuromeningeal tuberculosis. We conducted a retrospective study of 21 patients with neuromeningeal tuberculosis hospitalized in the Neurological Department between January 2002 and December 2016. Women were slightly more represented than men (SR=0.9), the age group between 20 and 40 years (47.61%) was predominant. The mean time between symptom onset and diagnosis was 25 days. Inaugural symptoms mainly included common signs (100%). Neurological signs included headache (61.90%), vomiting (47.61%) and motor deficit (33.33%). Lumbar puncture and brain CT scan were performed in 100% of cases. All patients received antibiotic therapy and corticosteroids. Outcome was favorable in 61.90% of cases, fatal in 9.52% of cases and marked by the persistence of neurological sequelae in 28.57% of cases. Neuromeningeal tuberculosis is an extremely polymorphic disease in its clinical and radiological manifestation. Early diagnosis and management is mainly associated with a favorable outcome.
本研究的目的是调查结核性脑脊膜炎患者的流行病学、临床、辅助检查、治疗及病情演变情况。我们对2002年1月至2016年12月间在神经科住院的21例结核性脑脊膜炎患者进行了一项回顾性研究。女性患者略多于男性（性别比=0.9），20至40岁年龄组占主导（47.61%）。症状出现至诊断的平均时间为25天。首发症状主要包括常见体征（100%）。神经系统体征包括头痛（61.90%）、呕吐（47.61%）和运动障碍（33.33%）。所有病例均进行了腰椎穿刺和脑部CT扫描。所有患者均接受了抗生素治疗和皮质类固醇治疗。61.90%的病例预后良好，9.52%的病例死亡，28.57%的病例有神经系统后遗症持续存在。结核性脑脊膜炎在临床和影像学表现上是一种极其多样的疾病。早期诊断和治疗主要与良好的预后相关。
