[二肽对被动皮肤过敏反应的抑制作用]
[Inhibition of passive cutaneous anaphylaxis by dipeptides].
作者信息
Ado A D, Alekseeva T A, Lukmanova F F
出版信息
Biull Eksp Biol Med. 1977 Oct;84(10):460-2.
PMID:912059
Abstract
The action of some dipeptides (Lalpha-alanyl-histidine, Lbeta-alanyl-histidine, histidyl-leicine and glycyl-histidine), and histidine on passive cutaneous anaphylaxis of guinea pigs was studied. Lbeta-alanyl-histidine (karnosine) and Lalpha-alanyl-histidine proved to inhibit the passive cutaneous anaphylaxis. Histidyl-leicine, glycyl-histidine, and histidine failed to produce any inhibitory effect on passive cutaneous anaphylaxis.
摘要
研究了某些二肽（Lα-丙氨酰组氨酸、Lβ-丙氨酰组氨酸、组氨酰亮氨酸和甘氨酰组氨酸）以及组氨酸对豚鼠被动皮肤过敏反应的作用。结果表明，Lβ-丙氨酰组氨酸（肌肽）和Lα-丙氨酰组氨酸可抑制豚鼠被动皮肤过敏反应。而组氨酰亮氨酸、甘氨酰组氨酸和组氨酸对豚鼠被动皮肤过敏反应未产生任何抑制作用。
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