Ruhnke M, Beyer J
Abteilung für Inneere Medizin, Virchow-Klinikum der Humbolds-Universität zu Berlin.
Med Klin (Munich). 1997 Jan 15;92(1):28-36. doi: 10.1007/BF03042279.
Fungal infections are of increasing importance in severely neutropenic and immunosuppressed patients because of their high incidence and their high mortality once systemic dissemination has occurred. Various prophylactic strategies have been developed that include environmental measures as well as topical and systemic antimycotic prophylaxis. In this review the causative pathogens and patients at risk for developing fungal infections will be identified. Specific strategies will be discussed for each patient population and suggestions made for areas of future research.
真菌感染在严重中性粒细胞减少和免疫抑制患者中日益重要,因为其发病率高,一旦发生全身播散,死亡率也高。已经制定了各种预防策略,包括环境措施以及局部和全身抗真菌预防。在本综述中,将确定引起真菌感染的病原体和有发生真菌感染风险的患者。将针对每个患者群体讨论具体策略,并对未来研究领域提出建议。