Bardenstein D S, Elmets C
Department of Ophthalmology, Case-Western Reserve University School of Medicine, Cleveland, OH, USA.
Ophthalmology. 1995 Jul;102(7):1031-4. doi: 10.1016/s0161-6420(95)30916-5.
Patients with the acquired immune deficiency syndrome are at risk for the development of multiple lesions of Molluscum contagiosum on the eyelids. In this setting, traditional methods of treatment frequently are ineffective and pose risks to the patient as well as to the treating physician.
A technique was developed that combined lidocaine/prilocaine topical anesthesia with hyperfocal cryotherapy. Twelve patients with multiple M. contagiosum lesions of the eyelids were treated. Initially, two methods were used: one application for 30 seconds or two applications for 20 seconds.
Lesions treated with two 20-second applications regressed. Most of those lesions treated for 30 seconds regressed. No scarring, lash complications, ptosis, or damage to the underlying cornea or deeper ocular structures was observed in any patient.
Hyperfocal cryotherapy is an effective therapy for multiple M. contagiosum lesions of the periorbital region, posing minimal risk to the patient and physician. It is particularly useful in patients who are positive for the human immunodeficiency virus, who frequently have multiple lesions, are likely to have recurrent disease, and who pose risks of disease transmission to the medical personnel caring for them.
获得性免疫缺陷综合征患者有发生眼睑多发性传染性软疣的风险。在这种情况下，传统治疗方法往往无效，且对患者和治疗医生均有风险。
开发了一种将利多卡因/丙胺卡因局部麻醉与超聚焦冷冻疗法相结合的技术。对12例眼睑多发性传染性软疣患者进行了治疗。最初，使用了两种方法：一次30秒或两次20秒。
接受两次20秒治疗的皮损消退。大多数接受30秒治疗的皮损也消退了。所有患者均未观察到瘢痕形成、睫毛并发症、上睑下垂或潜在角膜或更深层眼结构的损伤。
超聚焦冷冻疗法是治疗眶周多发性传染性软疣的有效方法，对患者和医生的风险最小。它对人类免疫缺陷病毒阳性患者特别有用，这些患者常有多个皮损，可能会复发疾病，并且有将疾病传播给照顾他们的医务人员的风险。
