眼内视网膜母细胞瘤眼球摘除术后眶内明胶海绵肉芽肿形成
Orbital avitene granuloma formation after enucleation for intraocular retinoblastoma.
作者信息
Abramson D H, Andracchi S
机构信息
New York Hospital/Cornell Medical Center, NY, USA.
出版信息
Am J Ophthalmol. 1997 Apr;123(4):567-9. doi: 10.1016/s0002-9394(14)70194-1.
PURPOSE
To report a case of orbital foreign body granuloma formation, mimicking tumor recurrence, secondary to the use of Avitene after enucleation for intraocular retinoblastoma.
METHODS
Eight months after undergoing enucleation for retinoblastoma, a 21-month-old boy underwent a biopsy of an orbital mass.
RESULTS
Histopathologic examination of the orbital biopsy specimen disclosed a proliferative granulomatous foreign body reaction surrounding multiple foci of a coarse fibrillar intercellular substance consistent with Avitene. No retinoblastoma cells were present.
CONCLUSION
A foreign body reaction should be included in the differential diagnosis of orbital mass lesions after surgery in which Avitene is used.
目的
报告1例眼内视网膜母细胞瘤眼球摘除术后使用明胶海绵后形成眼眶异物肉芽肿，酷似肿瘤复发的病例。
方法
一名21个月大的男孩在视网膜母细胞瘤眼球摘除术后8个月接受了眼眶肿物活检。
结果
眼眶活检标本的组织病理学检查显示，在多个与明胶海绵一致的粗大纤维状细胞间物质灶周围有增生性肉芽肿性异物反应。未见视网膜母细胞瘤细胞。
结论
在使用明胶海绵的手术后眼眶肿物病变的鉴别诊断中应考虑异物反应。
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