Lukish J, Denobile J, Kao T C, Blankenship C
Department of Surgery, National Naval Medical Center, Bethesda, Maryland 20889, USA.
Am Surg. 1997 Apr;63(4):338-40.
Twenty-one cases of primary small bowel malignant tumors treated at our institution from 1983 to 1993 were reviewed. The mean age at diagnosis was 51.6 +/- 16.8 years. Twelve patients (57%) reported symptoms of less than 1 month duration. Diagnosis was made at laparotomy in 13 patients (62%), and nine patients (43%) had three or more preoperative studies. Five patients (24%) presented with abdominal emergencies. The 5-year survival rate for the series was 19 per cent. This study was performed at a tertiary care military hospital where patients and physicians are not subjected to the financial constraints of civilian health care. This system should eliminate delays in seeking medical care and expedite diagnosis. Despite almost immediate medical attention for a majority of the patients, overall survival is not significantly different from that in previous reviews. This study emphasizes that the presentation of small bowel malignancies is indolent and difficult to diagnose. Prognosis remains poor despite the patient cost-free system and almost immediate medical attention. This study suggests that a high index of suspicion and a thorough evaluation, including laparotomy, are required to improve outcome.
对我院1983年至1993年收治的21例原发性小肠恶性肿瘤患者进行了回顾性研究。确诊时的平均年龄为51.6±16.8岁。12例患者(57%)报告症状持续时间不足1个月。13例患者(62%)在剖腹手术时确诊,9例患者(43%)术前进行了三项或更多检查。5例患者(24%)出现腹部急症。该组患者的5年生存率为19%。本研究在一家三级医疗军队医院进行,该医院的患者和医生不受平民医疗保健经济限制的影响。这种系统应能消除就医延误并加快诊断。尽管大多数患者几乎能立即得到医疗救治,但总体生存率与以往的综述相比并无显著差异。本研究强调,小肠恶性肿瘤的表现隐匿,难以诊断。尽管有免费的医疗系统且患者能几乎立即得到医疗救治,但其预后仍然很差。本研究表明,需要高度的怀疑指数和包括剖腹手术在内的全面评估,以改善治疗结果。