O'Boyle C J, Kerin M J, Feeley K, Given H F
Department of Surgery, University College Hospital, Galway, Republic of Ireland.
Ann R Coll Surg Engl. 1998 Sep;80(5):332-4.
Small intestinal malignancies are rare and may have a delayed presentation owing to insidious growth. We have reviewed the case notes of 25 patients presenting with primary small bowel tumours over a 10-year period. Abdominal pain, weight loss and vomiting were the most common symptoms. The median duration of symptoms was 6 months. Physical examination was normal in 24% of patients. An abdominal mass was present in 46% of cases. Emergency laparotomy was undertaken in 28% of patients. Lymphomas were identified in 72% and adenocarcinomas were present in 16%. The predominance of small bowel lymphoma is an unusual finding and may be related to the high incidence of coeliac disease in the region. The median survival in the lymphoma group was 36 months, which compares favourably with reported series.
小肠恶性肿瘤较为罕见,因其生长隐匿,症状可能出现较晚。我们回顾了10年间25例原发性小肠肿瘤患者的病例记录。腹痛、体重减轻和呕吐是最常见的症状。症状的中位持续时间为6个月。24%的患者体格检查正常。46%的病例可触及腹部肿块。28%的患者接受了急诊剖腹手术。72%的病例为淋巴瘤,16%为腺癌。小肠淋巴瘤占主导地位是一个不寻常的发现,可能与该地区腹腔疾病的高发病率有关。淋巴瘤组的中位生存期为36个月,与报道的系列研究相比情况较好。