响应营养物质耗尽时链球菌致热外毒素B（链球菌半胱氨酸蛋白酶）的瞬时产生。
Temporal production of streptococcal erythrogenic toxin B (streptococcal cysteine proteinase) in response to nutrient depletion.
作者信息
Chaussee M S, Phillips E R, Ferretti J J
机构信息
Department of Microbiology and Immunology, University of Oklahoma Health Sciences Center, Oklahoma City 73190, USA.
出版信息
Infect Immun. 1997 May;65(5):1956-9. doi: 10.1128/iai.65.5.1956-1959.1997.
Abstract
The effects of various growth conditions on the production of streptococcal erythrogenic toxin B (streptococcal pyrogenic exotoxin B [SPE B]) by Streptococcus pyogenes were analyzed. SPE B was detected in broth culture supernatant fluid only during the stationary phase of growth when glucose and other potential carbon sources were depleted from the medium. Additionally, SPE B production was inhibited when the concentration of glucose in the medium was maintained. These results suggest that SPE B is secreted under conditions of starvation and may be involved in nutrient acquisition.
摘要
分析了不同生长条件对化脓性链球菌产生链球菌致热外毒素B（链球菌热原性外毒素B [SPE B]）的影响。仅在生长稳定期，当培养基中的葡萄糖和其他潜在碳源耗尽时，才在肉汤培养上清液中检测到SPE B。此外，当培养基中葡萄糖浓度保持不变时，SPE B的产生受到抑制。这些结果表明，SPE B是在饥饿条件下分泌的，可能参与营养获取。
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