Safadi R, Ilan Y, Ashur Y, Shouval D
Division of Medicine, Hadassah University Hospital, Jerusalem, Israel.
Am J Gastroenterol. 1997 Apr;92(4):710-2.
A 54-yr-old man underwent orthotopic liver transplantation for cirrhosis caused by hepatitis C virus and associated with cryoglobulinemia and proteinuria. Four months after transplantation, the patient was reinfected with hepatitis C virus and cryoglobulinemia recurred, accompanied by increasing proteinuria, ascites, and pleural and pericardial effusion. Serum cryoglobulins and pleural and pericardial effusion disappeared rapidly following treatment with ribavirin, whereas proteinuria remain unchanged. We believe that pericardial effusion is an unusual presentation of hepatitis C virus-associated cryoglobulinemia.
一名54岁男性因丙型肝炎病毒引起的肝硬化并伴有冷球蛋白血症和蛋白尿接受了原位肝移植。移植后四个月，患者再次感染丙型肝炎病毒，冷球蛋白血症复发，同时蛋白尿增加，出现腹水以及胸腔和心包积液。使用利巴韦林治疗后，血清冷球蛋白以及胸腔和心包积液迅速消失，而蛋白尿保持不变。我们认为心包积液是丙型肝炎病毒相关冷球蛋白血症的一种不寻常表现。
