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[记忆障碍的临床类型及其诊断]

[Clinical types of memory disorders and their diagnosis].

作者信息

Yamadori A

机构信息

Section of Neuropsychology, Tohoku, University School of Medicine.

出版信息

Rinsho Shinkeigaku. 1996 Dec;36(12):1358-9.

PMID:9128409
Abstract

Three major types of amnesia, i.e. selective deficit of memory formation without disturbance of immediate memory have been recognized clinically. The hippocampal type is characterized by relatively short retrograde amnesia and preserved insight into his own amnesic trouble. Persistent amnesia is always associated with bilateral lesion. The diencephalon type usually shows longer retrograde amnesia and poor insight. Unilateral lesion is usually modal in deficit, i.e. verbal in the left and non-verbal in the right, and lacks clear evidence of retrograde amnesia. Responsible locus within the thalamus is still controversial. Our experience point to the mammilothalamic tract. The basal forebrain type is characterized by disorganized and confused recollection of the memorized items. Cued recall is fair compared to voluntary recall. Two special types of amnesic syndrome, i.e. transient global amnesia and isolated focal retrograde amnesia are also important clinical entities, although their etiologies and responsible lesions are not clear yet.

摘要

临床上已认识到三种主要类型的失忆症,即记忆形成的选择性缺陷而即时记忆不受干扰。海马型失忆症的特点是逆行性失忆相对较短,且对自己的失忆问题有自知之明。持续性失忆症总是与双侧病变相关。间脑型失忆症通常表现出较长时间的逆行性失忆,且自知力较差。单侧病变通常在缺陷方面具有模式性,即左侧为言语性,右侧为非言语性,且缺乏逆行性失忆的明确证据。丘脑内的责任部位仍存在争议。我们的经验指向乳头丘脑束。基底前脑型失忆症的特点是对记忆项目的回忆杂乱无章且混乱。与主动回忆相比,线索回忆尚可。两种特殊类型的失忆综合征,即短暂性全面性失忆症和孤立性局灶性逆行性失忆症,也是重要的临床病症,尽管它们的病因和责任病变尚不清楚。

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