Furuya E
Clin Chem. 1977 Nov;23(11):2136-8.
Erythromycin, phenazopyridine, methenamine mandelate, acetazolamide, and ascorbic acid reportedly interfere with the Porter-Silber reaction in the determination of urinary 17-hydroxycorticosteroids. Sodium bisulfite, added to the urine after hydrolysis with glucuronidase, removed almost all nonsteroidal interferences in urine from healthy adults medicated with the first three drugs, but such studies proved that acetazolamide and ascorbic acid do not interfere with the Porter--Silber reaction, whether or not sodium bisulfite is added.
据报道，红霉素、非那吡啶、孟德立胺、乙酰唑胺和抗坏血酸会干扰波特-西尔伯反应对尿17-羟皮质类固醇的测定。在用葡萄糖醛酸酶水解尿液后加入亚硫酸氢钠，可消除服用前三种药物的健康成年人尿液中几乎所有的非甾体干扰物，但此类研究证明，无论是否添加亚硫酸氢钠，乙酰唑胺和抗坏血酸均不会干扰波特-西尔伯反应。
