Christensson T
Clin Chim Acta. 1977 Nov 1;80(3):529-33. doi: 10.1016/0009-8981(77)90147-4.
A positive correlation was found between serum urate and elevated serum calcium in patients with hypercalcaemic primary hyperparathyroidism. No such correlation was detected in normocalcaemic controls, matched with respect to age and sex. Neither was such a correlation confirmed either in subjects with normalized serum calcium levels after extirpation of parathyroid adenomata, or in subjects with hypercalcaemia due to other conditions than primary hyperparathyroidism, such as various malignancies, sarcoidosis and hyperthyroidism. The positive correlation between elevated serum calcium and serum urate (within normal limits) in subjects with hypercalcaemic hyperparathyroidism is suggested in subjects with hypercalcaemic hyperparathyroidism is suggested to be a clue to the explanation of an association between hyperparathyroidism and urate retention.
在高钙血症原发性甲状旁腺功能亢进患者中，血清尿酸盐与血清钙升高之间存在正相关。在年龄和性别匹配的血钙正常对照组中未检测到这种相关性。在切除甲状旁腺腺瘤后血钙水平恢复正常的受试者中，或在因原发性甲状旁腺功能亢进以外的其他疾病（如各种恶性肿瘤、结节病和甲状腺功能亢进）导致高钙血症的受试者中，也未证实这种相关性。高钙血症性甲状旁腺功能亢进患者血清钙升高与血清尿酸盐（在正常范围内）之间的正相关被认为是解释甲状旁腺功能亢进与尿酸潴留之间关联的一个线索。
