Oyre S, Pedersen E M, Ringgaard S, Boesiger P, Paaske W P
Department of Cardiothoracic and Vascular Surgery T, Aarhus University Hospital, Skejby Sygehus, Denmark.
Eur J Vasc Endovasc Surg. 1997 Mar;13(3):263-71. doi: 10.1016/s1078-5884(97)80097-4.
To apply a new non-invasive method for quantification of in vivo wall shear stress (WSS) by magnetic resonance (MR) FAcE velocity mapping and measure WSS in the human abdominal aorta.
Prospective, open study.
Six volunteers.
MR FAcE velocity method was developed for measurements of mean, maximum, minimum WSS and oscillating shear index (OSI) values at the anterior and posterior walls of suprarenal and infrarenal abdominal aorta.
The mean, maximum and minimum WSS values were 0.63/0.28, 4.07/2.72 and -0.71/-1.00 N/m2, respectively, in the suprarenal/infrarenal aorta. The mean WSS was 0.35 N/m2 (p < 0.001) and the maximum WSS was 1.36 N/m2 (p < 0.0001) lower in the infrarenal aorta than in the suprarenal aorta. Mean, maximum minimum WSS and OSI values in the infrarenal position differed (p < 0.01) between the anterior and posterior walls.
WSS can be determined in vivo by MR FAcE velocity technique. Since the lowest WSS values were measured in the infrarenal, posterior blood-to-wall interface, the theory of more pronounced atherosclerosis development in low and oscillating WSS domains was not contradicted by the results of the present study.
应用一种新的非侵入性方法，通过磁共振（MR）FAcE速度成像定量测定体内壁面剪应力（WSS），并测量人体腹主动脉的WSS。
前瞻性开放研究。
6名志愿者。
开发MR FAcE速度成像方法，用于测量肾上腺上和肾上腺下腹主动脉前后壁的平均、最大、最小WSS以及振荡剪切指数（OSI）值。
肾上腺上/肾上腺下腹主动脉的平均、最大和最小WSS值分别为0.63/0.28、4.07/2.72和-0.71/-1.00N/m²。肾上腺下腹主动脉的平均WSS比肾上腺上主动脉低0.35N/m²（p<0.001），最大WSS低1.36N/m²（p<0.0001）。肾上腺下位置的平均、最大、最小WSS和OSI值在前壁和后壁之间存在差异（p<0.01）。
WSS可通过MR FAcE速度技术在体内测定。由于在肾上腺下的后壁血液与血管壁界面处测得的WSS值最低，本研究结果并未与低WSS和振荡WSS区域动脉粥样硬化发展更明显的理论相矛盾。
