Bentson J R
Clin Orthop Relat Res. 1977(127):111-9.
Metrizamide is an attractive myelographic agent with several advantages over other available myelographic agents. Radiographic detail is generally superior to Pantopaque and gas myelography, the material need not be aspiradted and does not appear to result in long-term complicaitons. Because of its low neuro-toxicity, it may be allowed to come into contact with the spinal cord and brain, unlike other water-soluble agents. Its main disadvantages are its tendency to diffuse into the CSF when run from one portion of the spinal canal to another and the occurrence of acute toxic effects such as vomiting and, rarely, seizures.
甲泛葡胺是一种有吸引力的脊髓造影剂，与其他现有的脊髓造影剂相比有几个优点。X线片细节通常优于碘苯酯和气体脊髓造影，该物质无需抽吸，且似乎不会导致长期并发症。由于其神经毒性低，与其他水溶性造影剂不同，它可以与脊髓和脑接触。其主要缺点是当从椎管的一部分注入到另一部分时，它有扩散到脑脊液中的倾向，以及会出现急性毒性作用，如呕吐，很少会出现癫痫发作。
