Ohtake N, Kanekura T, Kawamura K, Kanzaki T
Department of Dermatology, Kagoshima University Faculty of Medicine, Japan.
Am J Dermatopathol. 1997 Apr;19(2):185-8. doi: 10.1097/00000372-199704000-00014.
Unusual histopathologic structures were observed in lobular panniculitis of a patient with Behçet's disease. These were polyp-like in shape and protruded into cavities made of lysed fat cells. Various stages of development were observed. To determine the origin of cells making up these structures, we applied various histochemical and immunohistochemical techniques and found the cells to be histiocytes (macrophages) engaged in phagocytizing degenerated fat cells and cell membranes which had formed into membranocystic lesions.
在一名白塞病患者的小叶性脂膜炎中观察到异常的组织病理学结构。这些结构呈息肉样,突出到由溶解的脂肪细胞形成的腔中。观察到了不同的发育阶段。为了确定构成这些结构的细胞来源,我们应用了各种组织化学和免疫组织化学技术,发现这些细胞是参与吞噬已退化为膜性囊肿病变的脂肪细胞和细胞膜的组织细胞(巨噬细胞)。