Kato N, Matsue K
Department of Dermatology, Hokkaido University School of Medicine, Japan.
Am J Dermatopathol. 1997 Apr;19(2):189-96. doi: 10.1097/00000372-199704000-00015.
A case of follicular lymphomatoid papulosis (LyP) is reported. The patient was a 60-year-old Japanese woman. Clinically, cutaneous eruptions were reddish, centrally depressed, dome-shaped papules on the extensor aspect of the forearm. Histologically, they exhibited features that fulfilled the disease criteria described by Pierard, et al., i.e., (Am J Dermatopathol 1980;2:173-80), mixed cellular infiltrates including atypical Reed-Sternberg cell-like type-A cells and mycosis cell-like type-B cells surrounding hyperplastic follicular epithelia. The patient also showed many typical nonfollicular LyP papules, i.e., rhythmically recurrent papules which underwent spontaneous involution within a few weeks, over a 10-year period. The coincidental occurrence of a rare variant of follicular LyP and typical LyP in the same individual further suggests that follicular LyP is merely a histological pattern of LyP involving epithelial adnexae.
报告了一例滤泡性淋巴瘤样丘疹病（LyP）。患者为一名60岁的日本女性。临床上，皮肤损害为前臂伸侧发红、中央凹陷的圆顶状丘疹。组织学上，它们表现出符合皮耶拉尔等人描述的疾病标准的特征，即（《美国皮肤病病理学杂志》1980年；2：173 - 80），混合细胞浸润，包括非典型里德-斯腾伯格细胞样的A型细胞和蕈样霉菌病细胞样的B型细胞，围绕增生的滤泡上皮。在10年期间，该患者还出现了许多典型的非滤泡性LyP丘疹，即有节律地反复出现的丘疹，在几周内自行消退。同一患者中罕见的滤泡性LyP变体与典型LyP同时出现，进一步表明滤泡性LyP仅仅是LyP累及上皮附属器的一种组织学模式。
