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首例非侵入性可扩展内置假体的临床经验:一种用于患有恶性骨肿瘤儿童的保肢手术。

First clinical experience with a noninvasively extendable endoprosthesis: a limb-saving procedure in children suffering from a malignant bone tumor.

作者信息

Verkerke G J, Schraffordt Koops H, Veth R P, van Horn J R, Postma L, Grootenboer H J

机构信息

Centre for Biomedical Technology, University of Groningen, The Netherlands.

出版信息

Artif Organs. 1997 May;21(5):413-7.

PMID:9129775
Abstract

A modular endoprosthetic system that can be extended noninvasively has been applied for the first time in a growing child who underwent a tumor resection in his leg. The main goal of the study was to test the extendable mechanism that noninvasively corrects leg length differences caused by growth disturbances of the affected leg. The use of this endoprosthetic system resulted in good restoration of function. Six extensions were performed resulting in 19.5 mm of prosthetic growth. Unfortunately, an ingrown toenail caused infection of the endoprosthesis, and the infection necessitated extirpation of the prosthesis 15 months postoperatively. Two months later the patient died of acute leukemia. Analysis of the endoprosthesis revealed some manufacturing shortcomings, none of which impaired the function of the endoprosthesis.

摘要

一种可无创延长的模块化内置假体系统首次应用于一名腿部肿瘤切除术后仍在生长的儿童。该研究的主要目的是测试这种可无创矫正因患侧腿部生长紊乱导致的腿长差异的延长机制。这种内置假体系统的使用使功能得到了良好恢复。进行了6次延长,假体增长了19.5毫米。不幸的是,嵌甲导致了内置假体感染,术后15个月因感染不得不将假体摘除。两个月后,患者死于急性白血病。对内置假体的分析发现了一些制造缺陷,但这些缺陷均未影响内置假体的功能。

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