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同轴可延长膝关节使骨肉瘤患儿的肢体长度相等。

Coaxial extendible knee equalizes limb length in children with osteogenic sarcoma.

作者信息

Arkader Alexandre, Viola Dan C M, Morris Carol D, Boland Patrick J, Healey John H

机构信息

Orthopaedic Surgery Service, Department of Surgery, Memorial Sloan-Kettering Cancer Center, affiliated with Weill Medical College of Cornell University, New York, NY 10021, USA.

出版信息

Clin Orthop Relat Res. 2007 Jun;459:60-5. doi: 10.1097/BLO.0b013e3180514c37.

Abstract

We assessed our ability to achieve limb length equality (LLE) in children following limb-sparing surgery for distal femur osteogenic sarcoma using coaxial extendible prostheses in 12 children, averaging 11.6 years old at the time of tumor resection (range, 5.9-15.5 years). All but one child achieved clinical limb length equality. There were 23 extensions, averaging 3.8 extensions per patient (range, 1-5), by an average 13 mm per extension and an average total extension of 49.3 mm per patient extended. Eight children underwent revision surgery after an average of 45.1 months (range, 3-115 months). Aseptic loosening occurred more frequently among children with greater femoral diameter growth. The overall prosthetic survival was 60% at 3 years and 35% at 5 years. The survival until aseptic loosening at 3 and 5 years was 85% and 45%, respectively. Press-fit components survived longer than cemented stems. None of the devices loosened. At skeletal maturity the MSTS functional scores averaged 25. Using a coaxial extendible implant, we efficiently achieved LLE in this population. Prosthetic revision was needed frequently. Younger age and longer resection percentages were associated with shorter prosthetic survival and higher revision/aseptic loosening rates. Femoral diameter growth may contribute to loosening. Early experience with this extendible implant is promising.

摘要

我们评估了在12例儿童股骨远端骨肉瘤保肢手术后使用同轴可延长假体实现肢体长度相等(LLE)的能力,这些儿童在肿瘤切除时平均年龄为11.6岁(范围为5.9 - 15.5岁)。除1例儿童外,所有儿童均实现了临床肢体长度相等。共进行了23次延长,平均每位患者延长3.8次(范围为1 - 5次),每次延长平均13 mm,每位患者平均总延长49.3 mm。8例儿童在平均45.1个月(范围为3 - 115个月)后接受了翻修手术。在股骨直径增长较大的儿童中,无菌性松动更为常见。3年时假体总体生存率为60%,5年时为35%。3年和5年时直至无菌性松动的生存率分别为85%和45%。压配组件的存活时间比骨水泥柄更长。所有装置均未松动。骨骼成熟时,肌肉骨骼肿瘤学会(MSTS)功能评分平均为25分。使用同轴可延长植入物,我们在该人群中有效地实现了肢体长度相等。翻修手术频繁需要。年龄较小和切除比例较高与假体存活时间较短以及翻修/无菌性松动率较高相关。股骨直径增长可能导致松动。这种可延长植入物的早期经验很有前景。

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