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猪小肠黏膜下外部和内部神经丛的解剖

Dissection of the external and internal submucous plexuses of the pig small intestine.

作者信息

Thomsen L, Pearson G T

机构信息

Institute of Anatomy and Physiology, Royal Veterinary and Agricultural University, Copenhagen, Denmark.

出版信息

Kaohsiung J Med Sci. 1997 Jan;13(1):55-8.

PMID:9130823
Abstract

The submucous plexus of large mammals like dog, horse, cow, sheep, pig and man consists of more than one easily identified plexus. The divisions of the submucous plexus are known as the external submucous plexus and the internal submucous plexus. Recently findings have shown that there exists functional differences between the neuronal populations in the subdivisions of the submucous plexus in the small intestine of pigs. We report here how to obtain whole mounts of the submucous plexus containing both the internal and the external submucous plexus. The whole mounts from the submucous plexus of the pig contains almost no muscle and can be used in intracellular neuronal studies without adding nifedipine or equivalent L-type Ca2+ channel blockers to inhibit the contractions of the smooth muscle.

摘要

狗、马、牛、羊、猪和人类等大型哺乳动物的黏膜下神经丛由不止一个易于识别的神经丛组成。黏膜下神经丛的分支被称为外部黏膜下神经丛和内部黏膜下神经丛。最近的研究结果表明,猪小肠黏膜下神经丛各亚群中的神经元群体存在功能差异。我们在此报告如何获取包含内部和外部黏膜下神经丛的黏膜下神经丛整装标本。猪黏膜下神经丛的整装标本几乎不含肌肉,可用于细胞内神经元研究,而无需添加硝苯地平或等效的L型钙通道阻滞剂来抑制平滑肌收缩。

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