Dahm L S, Ewing C W, Harrison G M, Rucker R W
Chest. 1977 Nov;72(5):593-6. doi: 10.1378/chest.72.5.593.
One hundred fifty-three lung lavage procedures were performed on 81 cystic fibrosis patients during the years 1963 to 1976. Local analgesia was used in 24 lavages done via a rigid bronchoscope and in a group of 73 lavages directed by a fiberoptic bronchoscope. No abnormalities in cardiac rate or rhythm were observed with the lavages directed by fiberoptic bronchoscope. Fifty-six lavages were performed under general anesthesia with 20 cardiac abnormalities being noted among this group. Subjective improvement was noted in 96% of the 56 patients who had lavage under general anesthesia. Objective improvement was apparent in 45% of the 24 patients who had lavage with the rigid bronchoscope and 64% of the 36 patients who had lavage by fiberoptic bronchoscopy. It is concluded that patients with cystic fibrosis of varying stages of disability can more safety (and with good improvement) have bronchial washouts with the fiber-optic bronchoscope than with either of the other two techniques.
1963年至1976年间，对81例囊性纤维化患者进行了153次肺灌洗手术。24次通过硬支气管镜进行的灌洗以及73次由纤维支气管镜引导的灌洗采用了局部麻醉。在纤维支气管镜引导的灌洗过程中，未观察到心率或心律异常。56次灌洗在全身麻醉下进行，该组中有20例出现心脏异常。在56例接受全身麻醉下灌洗的患者中，96%有主观改善。在24例通过硬支气管镜进行灌洗的患者中，45%有客观改善；在36例通过纤维支气管镜进行灌洗的患者中，64%有客观改善。得出的结论是，不同残疾阶段的囊性纤维化患者使用纤维支气管镜进行支气管冲洗比使用其他两种技术中的任何一种更安全（且改善良好）。
