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氧化锰气溶胶慢性吸入毒性评估——I. 引言、实验设计和气溶胶生成方法

Evaluation of the chronic inhalation toxicity of a manganese oxide aerosol--I. Introduction, experimental design, and aerosol generation methods.

作者信息

Ulrich C E, Rinehart W, Busey W

出版信息

Am Ind Hyg Assoc J. 1979 Mar;40(3):238-44. doi: 10.1080/15298667991429534.

DOI:10.1080/15298667991429534
PMID:91319
Abstract

A brief literature review on manganese toxicity is presented; as related to designing a chronic inhalation study for evaluating methylcyclopentadienyl manganese tricarbonyl when utilized as a motor fuel additive. The experimental design of this study is described. The generation system utilized to simulate the manganese aerosol produced by an internal combustion engine is described in detail. This generation system operated twenty-four hours per day, seven days per week producing aerosols at 11.6, 112.5, and 1152 micrograms Mn/m3 with an aerodynamic diameter of approximately 0.11 micron.

摘要

本文简要回顾了锰毒性的相关文献;这与设计一项慢性吸入研究有关,该研究旨在评估用作发动机燃料添加剂的甲基环戊二烯三羰基锰。描述了本研究的实验设计。详细介绍了用于模拟内燃机产生的锰气溶胶的生成系统。该生成系统每周七天、每天二十四小时运行,产生空气动力学直径约为0.11微米、浓度分别为11.6、112.5和1152微克锰/立方米的气溶胶。

相似文献

1
Evaluation of the chronic inhalation toxicity of a manganese oxide aerosol--I. Introduction, experimental design, and aerosol generation methods.氧化锰气溶胶慢性吸入毒性评估——I. 引言、实验设计和气溶胶生成方法
Am Ind Hyg Assoc J. 1979 Mar;40(3):238-44. doi: 10.1080/15298667991429534.
2
The health implications of increased manganese in the environment resulting from the combustion of fuel additives: a review of the literature.燃料添加剂燃烧导致环境中锰含量增加对健康的影响:文献综述
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Evaluation of the chronic inhalation toxicity of a manganese oxide aerosol. III. Pulmonary function, electromyograms, limb tremor, and tissue manganese data.氧化锰气雾剂慢性吸入毒性的评估。III. 肺功能、肌电图、肢体震颤及组织锰数据。
Am Ind Hyg Assoc J. 1979 May;40(5):349-53. doi: 10.1080/15298667991429688.
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Evaluation of the chronic inhalation toxocity of a manganese oxide aerosol. II. Clinical observations, hematology, clinical chemistry and histopathology.氧化锰气溶胶慢性吸入毒性的评估。II. 临床观察、血液学、临床化学和组织病理学。
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Environmental effects and exposures to manganese from use of methylcyclopentadienyl manganese tricarbonyl (MMT) in gasoline.环境影响以及因汽油中使用甲基环戊二烯基三羰基锰(MMT)而接触锰的情况。
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Changes in manganese and lead in the environment and young children associated with the introduction of methylcyclopentadienyl manganese tricarbonyl in gasoline--preliminary results.汽油中引入甲基环戊二烯三羰基锰后环境及幼儿体内锰和铅的变化——初步结果
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1
Changes in the redox state of neuroblastoma cells after manganese exposure.
Arch Toxicol. 1983 Sep;54(1):53-9. doi: 10.1007/BF00277815.