Dahlmann W, Volles E, Lüderitz B
Dtsch Med Wochenschr. 1977 Oct 28;102(43):1555-9. doi: 10.1055/s-0028-1105537.
A 39-year-old woman developed generalised paralysis, reversible organic brain syndrome, and cardiac dysrhythmias after 15 years of laxative abuse. Under continuous and cautious administration of potassium the cardiac rhythm became normal within four days and two days later the paralysis and organic brain syndrome almost disappeared. The cause of the psychiatric symptoms is thought to be cerebral potassium deficiency and an abnormal sodium/potassium equilibrium. Other clinical signs and symptoms due to extreme potassium depletion are presented. The importance of Na+/K+-activated membrane ATP-ase in myocardium and CNS is discussed.
一名39岁女性在滥用泻药15年后出现全身麻痹、可逆性器质性脑综合征和心律失常。在持续谨慎补钾的情况下，四天内心律恢复正常，两天后麻痹和器质性脑综合征几乎消失。精神症状的原因被认为是脑钾缺乏和钠/钾平衡异常。文中还介绍了极度钾缺乏导致的其他临床体征和症状。并讨论了钠钾激活的膜ATP酶在心肌和中枢神经系统中的重要性。
