Mertz K J, Levine W C, Mosure D J, Berman S M, Dorian K J
Division of STD Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Sex Transm Dis. 1997 Mar;24(3):169-75. doi: 10.1097/00007435-199703000-00009.
Evaluation of existing testing programs should guide the national effort to expand programs for the prevention of chlamydial infections. The Columbus (Ohio) Health Department instituted community-wide testing for Chlamydia trachomatis in 1988.
To assess trends in the prevalence of chlamydial infection, the coverage of screening, and concurrent trends in the prevalence of gonorrhea.
This was a cross-sectional study of women 15 to 44 years of age tested for C. trachomatis at over 50 provider sites in Columbus, Ohio, from 1989 to 1992.
The prevalence of chlamydial infection among all women tested decreased by 33% from 1989 to 1992. Prevalence decreased least (19%) among black women 15 to 19 years of age, the group with the highest initial prevalence (20.2%), even though 42% of this population in the city was tested. Prevalence did not decrease at all among prenatal patients 15 to 19 years of age. For women tested for both gonorrhea and chlamydia, gonorrhea decreased by 39% during the 4-year period.
Screening appeared to have limited effect on the prevalence of chlamydial infection for groups with highest initial prevalence, despite the relatively high percentage of the population tested. Expanding screening programs to include men and instituting behavioral interventions may be necessary to reduce more rapidly the prevalence of chlamydia among these women.
对现有检测项目的评估应指导全国为扩大衣原体感染预防项目所做的努力。俄亥俄州哥伦布市卫生部门于1988年开展了全市范围的沙眼衣原体检测。
评估衣原体感染患病率的趋势、筛查覆盖率以及淋病患病率的同期趋势。
这是一项横断面研究,研究对象为1989年至1992年期间在俄亥俄州哥伦布市50多个医疗机构接受沙眼衣原体检测的15至44岁女性。
在所有接受检测的女性中,衣原体感染患病率从1989年到1992年下降了33%。初始患病率最高(20.2%)的15至19岁黑人女性患病率下降最少(19%),尽管该城市这一年龄段人群中有42%接受了检测。15至19岁的产前患者中,患病率根本没有下降。对于同时接受淋病和衣原体检测的女性,淋病患病率在4年期间下降了39%。
尽管接受检测的人群比例相对较高,但筛查对初始患病率最高的人群中衣原体感染患病率的影响似乎有限。有必要扩大筛查项目以纳入男性并开展行为干预,以便更快地降低这些女性中的衣原体感染患病率。