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[腺瘤样增生的宫腔镜诊断与随访及治疗结果]

[Hysteroscopic diagnosis and follow-up of adenomatous hyperplasia and therapeutic consequences].

作者信息

Schmidt T, Römer T, Schwesinger G, Lorenz G

机构信息

Klinik für Frauenheilkunde und Geburtshilfe, Ernst-Moritz-Arndt-Universität Greifswald.

出版信息

Zentralbl Gynakol. 1997;119(1):12-5.

PMID:9133142
Abstract

63 cases of adenomatous endometrial hyperplasia (1st-3rd degree) were diagnosed by hysteroscopy and D&C at the Department of Obstetrics and Gynaecology of the University of Greifswald from January 1991 to December 1994. In 40 patients with adenomatous hyperplasia (2nd-3rd degree) a hysterectomy was performed. 23 patients presenting with 1st degree hyperplasia were treated continuously with gestagenes for a period of 6 months. In those cases we performed a repeated diagnostic hysteroscopy and D&C to check the success of hormonal treatment. In 92.5% of tall cases the histological diagnoses of a lower degree adenomatous hyperplasia, cystic glandular hyperplasia or of a normal endometrium were made after hysterectomy. Only in one patient (2.5%) an endometrial carcinoma developed from an adenomatous hyperplasia (3rd degree). There was no progression to observe of adenomatous hyperplasia after hormonal therapy with gestagenes. We conclude that in those cases a hysterectomy has not necessarily to be carried out. However, in adenomatous hyperplasia of 3rd degree hysterectomy has to be the treatment of choice, because there is an increased risk of invasion.

摘要

1991年1月至1994年12月期间,在格赖夫斯瓦尔德大学妇产科,通过宫腔镜检查和刮宫术诊断出63例子宫内膜腺瘤样增生(1 - 3级)。40例腺瘤样增生(2 - 3级)患者接受了子宫切除术。23例表现为1级增生的患者连续接受孕激素治疗6个月。在这些病例中,我们进行了重复的诊断性宫腔镜检查和刮宫术,以检查激素治疗的效果。在92.5%的病例中,子宫切除术后组织学诊断为较低程度的腺瘤样增生、囊性腺性增生或正常子宫内膜。只有1例患者(2.5%)腺瘤样增生(3级)发展为子宫内膜癌。孕激素激素治疗后未观察到腺瘤样增生进展。我们得出结论,在这些病例中不一定必须进行子宫切除术。然而,对于3级腺瘤样增生,子宫切除术必须是首选治疗方法,因为侵袭风险增加。

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